When a webpage in your application detects changes made to input items (if they are valid or not), it will present the user a popup asking if he/she wants to leave the page or stay on the page. Although that is useful in many cases, sometimes you just want to switch it off on a specific page. The solution is really easy.
Place the following Javascript in the onLoad event of your page:
window.onbeforeunload = null;
In for instance, Application Express, you can put it in the Execute when page loads item in the Javascript section of your page.
If you want to show a different message, just replace the null with the message between double quotes.